Role of total antioxidant capacity and oxidative stress in fertilization and embryo selection in the IVF cycle

Purpose: This study aims to evaluate the oxidant and antioxidant parameters in follicular fluid embryo culture medium IVF cycles investigate their effects on quality, fertilization success, pregnancy.
 Materials Methods: Fifty-one patients who underwent IVF/ICSI were included this prospective study. Two hundred sixty of a total 454 fluids cell media transferred fifty-one embryos (one from each patient) examined. Antioxidant activity (AOA), Trolox equivalent capacity (TEAC), thiobarbiturate reactive substances (TBARS), ferric power (FRAP), paraoxonase, nitrotyrosine analyzed.
 Results: TBARS significantly lower fertilized oocytes than non-fertilized (21 vs. 29.75 nmol/ml). There was no difference terms other parameters. TEAC levels higher agonist protocol group antagonist group. In there differences between groups any analysis. that became pregnant after transfer second day. 
 Conclusion: When oxidative stress evaluated both follicle medium, it determined lipid peroxidation negatively affected fertilization. However, is significant quality pregnancy rates.